放射線治療におけるセットアップマージンに関する検討: どれだけの照合数と患者数が必要か

  • 松本 光弘
    大阪大学大学院医学系研究科保健学専攻医用物理工学講座
  • 太田 誠一
    大阪大学医学部附属病院医療技術部放射線部門
  • 大野 吉美
    広島大学医学部附属病院診療支援部放射線治療部門
  • 小縣 裕二
    大阪大学大学院医学系研究科保健学専攻機能診断科学講座

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タイトル別名
  • Study of Setup Margins in Radiation Therapy: How Many Verification Times and Patients are Required
  • ホウシャセン チリョウ ニ オケル セットアップマージン ニ カンスル ケントウ ドレダケ ノ ショウゴウスウ ト カンジャスウ ガ ヒツヨウ カ

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Introduction: The purpose of this research is to require suitable numbers of verification times and patients for calculating the setup margin (SM) in radiotherapy. Methods: 1) This simulation was performed using the standard normal distribution random number. The simulation used the seven levels of verification from 5 to 35 in 5 steps, and 35 patients. 2) The setup error in prostate radiotherapy at three hospitals was analyzed. Systematic error and random error were calculated from each patient’s average value and standard deviation. Furthermore, we used the formula of J Stroom to calculate SM. Suitable numbers of verification times and patients were obtained from statistical analysis of the simulated results. Results: 1) In the results of our simulations using random number, SM converged on 1.0 to 1.3 mm, regardless of the number of patients, when there were more than 15 verification times; 2) The results of clinical data were slightly different from the standard normal distribution, and more than 15 verification times and over 15 patients were required. Conclusions: In conclusion, calculation of the SM in radiotherapy required more than 15 verification times and over 15 patients.

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