Phase-sensitive Inversion-recovery(PSIR)を用いた子宮ダイナミックスタディのための基礎検討

  • 高津 安男
    大阪赤十字病院放射線診断科部 金沢大学大学院医薬保健学総合研究科保健学専攻
  • 茂木 俊一
    城西クリニック放射線科 群馬大学大学院医学系研究科放射線診断核医学分野
  • 宮地 利明
    金沢大学大学院医薬保健学総合研究科保健学専攻
  • 山村 憲一郎
    金沢大学大学院医薬保健学総合研究科保健学専攻 大阪医科大学附属病院中央放射線部

書誌事項

タイトル別名
  • An Examination for Uterine Dynamic Study with Phase-sensitive Inversion-recovery
  • 臨床技術 Phase-sensitive Inversion-recovery (PSIR)を用いた子宮ダイナミックスタデイのための基礎検討
  • リンショウ ギジュツ Phase-sensitive Inversion-recovery (PSIR)オ モチイタ シキュウ ダイナミックスタデイ ノ タメ ノ キソ ケントウ

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説明

The depth of myometrial invasion in patients with endometrial carcinoma is recognized as an important factor that closely correlates with prognosis. Preoperative assessment of myometrial invasion is essential for planning surgery. To enhance the contrast between myometrium and endometrium including myometrial invasion with endometrial carcinoma, we optimized the sequence parameter with phase-sensitive inversion-recovery (PSIR) in gadolinium dynamic study of uterine corpus. On a 1.5-T magnetic resonance imaging (MRI), images were acquired by three-dimensional (3D) T1 -turbo fieldecho (TFE) with PSIR sequence and gadolinium-diethylenetriamine pentaacetic acid( Gd-DTPA) dilutedphantom (0-5 mmol/L) and myometrium model (manganese chloride tetrahydrate+agar). We calculatedthe null point andthe contrast-to-noise ratio (CNR) at multiple TFE inversion delay times, 200 ms-maximum in each combination; flip angles (FAs), 5-35 degrees; TFE factor, 20-40; andshot interval (SI), 500-1000 ms. We assumed that dynamic scanning time was 30 seconds when the sensitivity encoding factor was 2, namely, in this study, the scanning time was 1 minute with no sensitivity encoding. In addition, we comparedCNR between optimizedPSIR sequence ande-Thrive. We recognizeda successful CNR of the 3D PSIR parameter was TFE inversion delay times, 335 ms; FA, 25 degrees; TFE factor, 20; and SI, 500 ms. In each gadolinium-DTPA diluted phantom, the average CNR of the optimized PSIR sequence was approximately 1.7 times (maximum: 3 times) higher than e-Thrive. Optimizing sequence parameter of PSIR is applicable in gadolinium dynamic study of uterine corpus.

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