The Effect of the Surroundings to the Apparent Diffusion Coefficient on Diffusion Weighted Imaging

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  • Yamatani Yuya
    Central Division of Radiology, Nara Medeical University Hospital
  • Doi Tsukasa
    Division of Radiology, Department of Medical Technology, Osaka University Hospital
  • Shimizu Kozo
    Central Division of Radiology, Nara Medeical University Hospital
  • Nogi Akihiro
    Central Division of Radiology, Nara Medeical University Hospital

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Other Title
  • 拡散強調画像における測定対象周囲の環境変化がみかけの拡散係数に与える影響
  • カクサン キョウチョウ ガゾウ ニ オケル ソクテイ タイショウ シュウイ ノ カンキョウ ヘンカ ガ ミカケ ノ カクサン ケイスウ ニ アタエル エイキョウ

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Abstract

Diffusion weighted imaging (DWI) is now widely used in magnetic resonance (MR) imaging of the head and body. Moreover, the Apparent diffusion coefficient (ADC) value is often used for the differential diagnosis of the tumor. However, the effect of the surroundings on the ADC value has not been reported. In this study, we used the phantom completely sealed up to measure the change in the ADC value depending on the surroundings material. The results showed that the ADC value decreased according to the density of superparamagnetic iron oxide (SPIO) in the surroundings. Clinically, hemorrhage or iron deposit around the tumor may affect the ADC value of the tumor and result in under-estimation.

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