ラット下垂体前葉PAS陽性細胞の季節別観察

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  • Observations on the seasonal changes of the PAS-positive cells in the rat anterior hypoyhysis
  • ラット カスイタイ ゼン ヨウ PAS ヨウセイ サイボウ ノ キセツ ベツ カンサツ

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According to the consideration that glycoprotein hormones such as TSH, FSH and LH or their transmitters may be revealed by PAS-granules in the β cell of the anterior hypophysis, I monthly observed the changes of the pituitary PAS-positive cells in male matured rats, which had been fed under the condition of room temperature in Osaka (3°C-32°C). And these observations were compared with the changes under the exposure to heat (32°C-34°C) and cold (2°C).<br>In winter, the cells containing PAS-positive granules presented various degrees of degranulation in the PAS-stained sections and two cases of them were observed like “T-cell”. In summer, the sections showed that PAS-positive cells were atrophic. The results of the exposed cases to heat and cold corresponded with that of monthly observed cases. From the present observation it could not be possible to identify “thyrotrophs”, “FSH gonadotrophs” and “LH gonadotrophs” respectively. But, it was noticed that these changes seemed to be more sensitive in the central zone of the anterior lobe than in the so-called “sex-zone”, and in the exposure to cold PAS-positive cells increased in the central zone.

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