Carotid Plaque Assessment Using Inversion Recovery T<sub>1</sub> Weighted-3 Dimensions Variable Refocus Flip Angle Turbo Spin Echo Sampling Perfection with Application Optimized Contrast Using Different Angle Evolutions Black Blood Imaging

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  • Inversion Recovery併用T<sub>1</sub>強調-3D Variable Refocus Flip Angle Turbo Spin Echo(SPACE)Black Blood Imagingの 頸動脈プラーク検査への応用
  • 臨床技術 Inversion Recovery併用T₁強調-3D Variable Refocus Flip Angle Turbo Spin Echo (SPACE) Black Blood Imagingの頸動脈プラーク検査への応用
  • リンショウ ギジュツ Inversion Recovery ヘイヨウ T ₁ キョウチョウ-3D Variable Refocus Flip Angle Turbo Spin Echo (SPACE) Black Blood Imaging ノ ケイドウミャク プラーク ケンサ エ ノ オウヨウ
  • Carotid Plaque Assessment Using Inversion Recovery T1 Weighted-3 Dimensions Variable Refocus Flip Angle Turbo Spin Echo Sampling Perfection with Application Optimized Contrast Using Different Angle Evolutions Black Blood Imaging

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Abstract

Vulnerable plaque can be attributed to induction of ischemic symptoms and magnetic resonance imaging of carotid artery is valuable to detect the plaque. Magnetization prepared rapid acquisition with gradient echo (MPRAGE) method could detect hemorrhagic vulnerable plaque as high intensity signal; however, blood flow is not sufficiently masked by this method. The contrast for plaque in T1 weighted image (T1WI) could not be obtained sufficiently with black blood image (BBI) by sampling perfection with application optimized contrast using different angle evolutions (SPACE) method as turbo spin echo (TSE). In addition, an appearance of artifact by slow flow is a problem. Considering these controversial situations in plaque imaging, we examined the modified BBI inversion recovery (IR)-SPACE in which IR was added for SPACE method so that the contrast for plaque in T1WI was optimized. We investigated the application of this method in plaque imaging. As a result of phantom imaging, the contrast for plaque in T1WI was definitely obtained by choosing an appropriate inversion time (TI) for the corresponding repetition time. In clinical cases, blood flow was sufficiently masked by IR-SPACE method and the plaque imaging was clearly obtained in clinical cases to the same extent as MPRAGE method. Since BBI with IR-SPACE method was derived from both IR pulse and flow void effect, this method could obtain the blood flow masking effect definitely. The present study suggested that SPACE method might be applicable to estimate properties of carotid artery plaque.

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