Sister Chromatid Exchanges in Lymphocytes and Smoking Habits

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  • リンパ球姉妹染色分体交換と喫煙習慣
  • リンパキュウ シマイ センショク ブンタイ コウカン ト キツエン シュウカン

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Abstract

We analyzed sister chromatid exchange (SCE) frequency in lymphocytes in 39 non-smokers and 29 smokers. Non-smokers had 9.9±1.5 SCEs/cell (mean±s. d.), and smokers had 11.4±1.9 SCEs/cell. The difference was statistically significant (p<0.001). The SCE frequency in smokers was dependent on the number of cigarettes smoked per day. We think that SCE frequency in lymphocytes is useful for evaluation of environmental mutagens.

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