CT‐transmissionの呼吸管理がPET/CTの融合精度に与える影響―600人を対象とした標準呼気と自由呼吸の比較―

  • 大澤 敦
    財団法人癌研究会癌研有明病院放射線部核医学チーム
  • 滝口 智洋
    財団法人癌研究会癌研有明病院放射線部核医学チーム
  • 田村 慎太郎
    財団法人癌研究会癌研有明病院放射線部核医学チーム
  • 大橋 聖
    財団法人癌研究会癌研有明病院放射線部核医学チーム
  • 三輪 建太
    財団法人癌研究会癌研有明病院放射線部核医学チーム
  • 秋本 健太
    財団法人癌研究会癌研有明病院放射線部核医学チーム
  • 我妻 慧
    財団法人癌研究会癌研有明病院放射線部核医学チーム

書誌事項

タイトル別名
  • Respiratory Management of CT-transmission for Accuracy Fusion in PET/CT: A Comparison between Normal Expiration and Free Breathing in 600 Experiences
  • 臨床技術 CT-transmissionの呼吸管理がPET/CTの融合精度に与える影響--600人を対象とした標準呼気と自由呼吸の比較
  • リンショウ ギジュツ CT transmission ノ コキュウ カンリ ガ PET CT ノ ユウゴウ セイド ニ アタエル エイキョウ 600ニン オ タイショウ ト シタ ヒョウジュン コキ ト ジユウ コキュウ ノ ヒカク

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抄録

Image misregistration can occur in fusion PET/CT, because of motion artifacts caused by the management of respiration. The standard imaging protocol of the CT component of PET/CT is normal expiration (NormExp) or free breathing (FB). The objective of this study was to compare NormExp and FB for the optimal breathing protocol for PET/CT scans. A total of 600 consecutive patients were examined using lutetium oxyorthosilicate (LSO)-based PET/CT. CT was acquired during NormExp (i.e., the level reached when the patient exhaled without forcing expiration and then held the breath) in 300 patients and during FB in 300 patients. The profile of liver measured along body axis was assessed. The distance of profile centers between the PET image and the CT image was measured. The misalignment between profile centers (PET) and profile centers (CT) was compared between NormExp and FB using the histogram of patients. An F test was used to test if the variances of two misalignments are equal. Next, the relationship between misalignment and age was evaluated in two managements of respiration. There was no significant difference between NormExp and FB in the histogram. However, significant misalignments (>10 cm) were found with NormExp. Patient age may have influenced the mismatch. FB is recommended for geriatric patients during acquisition of attenuation correction CT data sets.

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