逐次近似応用CT 再構成を用いた低吸収域の検出能評価―超急性期脳梗塞評価用ファントムの開発および解析―

DOI Web Site Web Site PubMed 参考文献4件
  • 西村 一晃
    市立ひらかた病院放射線科
  • 田中 千香子
    大阪大学医学部附属病院医療技術部放射線部門
  • 深尾 真理
    大阪大学医学部附属病院医療技術部放射線部門
  • 上口 貴志
    情報通信研究機構脳情報通信融合研究センター 大阪大学大学院生命機能研究科 大阪大学大学院医学系研究科
  • 西澤 光生
    大阪医科大学放射線医学教室

書誌事項

タイトル別名
  • The Detectability of Iterative CT Reconstruction for Low-contrast Lesions in Hyperacute Cerebral Infarction: Assessment with Newly Developed Dedicated Head Phantoms
  • チクジ キンジ オウヨウ CT サイコウセイ オ モチイタ テイキュウシュウイキ ノ ケンシュツノウ ヒョウカ : チョウキュウセイキ ノウ コウソク ヒョウカヨウ ファントム ノ カイハツ オヨビ カイセキ

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Iterative reconstruction techniques, such as adaptive statistical iterative reconstruction (ASiR), improve the contrast-to-noise ratio of computed tomography (CT) images; however, underlying anatomical structures may nevertheless hamper detectability of low-contrast areas in clinical situations, despite using such a technique. We therefore conducted a phantom study to investigate the efficacy of ASiR in improving the detectability of low-contrast areas in the presence of brain anatomical structures. We developed dedicated head phantoms simulating hyperacute cerebral infarction and confirmed that their CT numbers were sufficiently reproducible and that observer performance in detecting low-contrast areas using these phantoms more closely resembled that in clinical situations than that using a simple phantom. The efficacy of ASiR in improving low-contrast detectability was evaluated via receiver operating characteristics analysis. The mean area under the curve (AUC) values at ASiR blend rates of 0%, 30%, 60%, and 100% were 0.57, 0.57, 0.59, and 0.59 at 200 mA; 0.83, 0.84, 0.84, and 0.90 at 500 mA; and 0.79, 0.77, 0.76, and 0.79 at 800 mA, respectively. No significant differences were noted in AUC values among ASiR blend rates at any mA setting, suggesting that ASiR does not improve the detectability of subtle low-contrast lesions seen in hyperacute cerebral infarction in clinical situations.

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