Skin Sensitizers in Cosmetics and Skin Care Products
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- MINAMOTO Keiko
- Department of Preventive and Environmental Medicine, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University
Bibliographic Information
- Other Title
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- 化粧品,医薬部外品成分中の皮膚感作性物質と接触皮膚炎
- ケショウヒン イヤク ブガイヒン セイブン チュウ ノ ヒフ カンサセイ ブッシツ ト セッショク ヒフエン
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Description
Cosmetics are defined as “articles with mild action on the human body, which are intended to be applied to the human body through rubbing, sprinkling or other methods, aiming to clean, beautify and increase the attractiveness, alter the appearance or to keep the skin or hair in good condition (The Pharmaceutical Affairs Law: Article 2).” Consequently, they include personal hygiene products such as shampoos, soaps and toothpaste. In Europe, 1% of the population is estimated to be allergic to fragrances and 2–3% to ingredients of cosmetics; 10% of outpatients patch-tested for cosmetics allergy were found to be positive. Allergenic ingredients of cosmetics can be fragrances, hair dye, preservatives, antioxidants, emollients, surfactants, UV absorbers, pigments or resins used in nail cosmetics. Among standard allergen series, eight substances are related to cosmetics; in Japan in 2003, p-phenylenediamine (hair dyes) induced allergic reactions with the highest rate of 7.9% in outpatients patch-tested (n=805), followed by fragrance mix No. 1 (4.0%, mixture of eight fragrances frequently used), colophony (3.2%, main contents of pine resin), lanolin alcohol (2.7%,emollients), and formaldehyde, parabens, Kathon CG (2.7% ,1.9% and 1.0%, respectively; preservatives). Cosmetic allergy symptoms tend to be mild except those caused by hair dye. However, the population exposed to cosmetics is huge and the number of ingredients used in cosmetics increased up to more than 6000. Here, major cosmetic ingredient allergens, mainly reported in Japan, are reviewed and discussed.<br>
Journal
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- Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)
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Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) 65 (1), 20-29, 2010
The Japanese Society for Hygiene
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Details 詳細情報について
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- CRID
- 1390001206363816704
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- NII Article ID
- 10027649950
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- NII Book ID
- AN00185923
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- COI
- 1:CAS:528:DC%2BC3cXit1KmsLc%3D
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- ISSN
- 18826482
- 00215082
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- NDL BIB ID
- 10576484
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- PubMed
- 20134105
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL Search
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed