Investigation of simplified international diagnostic criteria for autoimmune hepatitis

DOI 2 Citations 29 References
  • KANEKO Akira
    Department of Gastroenterology, NTT West Osaka Hospital
  • KUBO Mitsuhiko
    Department of Gastroenterology, NTT West Osaka Hospital
  • YAMADA Ryoko
    Department of Gastroenterology, NTT West Osaka Hospital
  • TANIMURA Tomoki
    Department of Gastroenterology, NTT West Osaka Hospital
  • YAMAGUCHI Daisuke
    Department of Gastroenterology, NTT West Osaka Hospital
  • YAMAMOTO Moritoshi
    Department of Gastroenterology, NTT West Osaka Hospital
  • TATSUMI Nobuyuki
    Department of Gastroenterology, NTT West Osaka Hospital
  • NAKAMA Akihiro
    Department of Gastroenterology, NTT West Osaka Hospital
  • MITA Eiji
    Department of Gastroenterology, National Hospital Organization Osaka National Hospital
  • KATO Michio
    Department of Internal Medicine, National Hospital Organization Minami Wakayama Medical Center
  • HIJIOKA Taizo
    Department of Gastroenterology, National Hospital Organization Osaka Minami Medical Center
  • OSHITA Masahide
    Department of Internal Medicine, Osaka Police Hospital
  • ITO Toshifumi
    Department of Internal Medicine, Osaka Koseinenkin Hospital
  • IMANAKA Kazuho
    Department of Hepatobiliary and Pancreatic Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
  • KATAYAMA Kazuhiro
    Department of Hepatobiliary and Pancreatic Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
  • SATO Masako
    Department of Gastroenterology, Osaka Rosai Hospital
  • YOSHIHARA Harumasa
    Department of Gastroenterology, Osaka Rosai Hospital
  • KIRIYAMA Kazuo
    Department of Internal Medicine, Ashiya Municipal Hospital
  • IMAI Yasuharu
    Department of Gastroenterology, Ikeda Municipal Hospital
  • KASHIHARA Takeshi
    Department of Gastroenterology, Itami City Hospital
  • FUKUI Hiroyuki
    Department of Gastroenterology, Yao Municipal Hospital
  • SUZUKI Kunio
    Department of Internal Medicine, Saiseikai Senri Hospital
  • MIYOSHI Shio
    Department of Internal Medicine, Senrichuo Hospital
  • YAMADA Akira
    Department of Gastroenterology, Sumitomo Hospital
  • YAKUSHIJIN Takayuki
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • MOCHIZUKI Kiyoshi
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • HIRAMATSU Naoki
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • TAKEHARA Tetsuo
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • HAYASHI Norio
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine

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Other Title
  • 自己免疫性肝炎の新しい国際診断基準の検証

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The simplified international diagnostic criteria for autoimmune hepatitis (AIH), re-revised by the International AIH Group in 2008, were investigated in 114 patients with AIH from 15 centers in Japan. While applying of the criteria, we had to pay attention to anti-nuclear antibody measurement methods, and liver histology scoring. Definite and probable AIH were diagnosed in 83 and 22 patients, respectively. The criteria were found to be useful for the diagnosis of AIH in Japan. However, 9 patients who did not meet the diagnostic criteria showed normal immunoglobulin G levels or were negative for autoantibodies. As the criteria were unreliable for diagnosing such atypical cases in the present series, we speculated that we should not rely solely on these, criteria and take a more holistic approach to diagnosis in such cases.<br>

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