Multiple gastrointestinal stromal tumors during nilotinib treatment for chronic myelogenous leukemia in a patient with neurofibromatosis type 1
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- SHUGO Haruhiko
- Department of Gastroenterology, Municipal Tsuruga Hospital
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- HODO Yuji
- Department of Gastroenterology, Municipal Tsuruga Hospital
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- WATANABE Takeshi
- Department of Surgery, Municipal Tsuruga Hospital
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- UWAFUJI Seiko
- Department of Surgery, Municipal Tsuruga Hospital
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- SUGIMORI Junji
- Department of Surgery, Municipal Tsuruga Hospital
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- HAYASHI Yasuo
- Department of Surgery, Municipal Tsuruga Hospital
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- HARADA Kenichi
- Department of Human Pathology, Kanazawa University Graduate School of Medicine
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- NAKANUMA Yasuni
- Department of Human Pathology, Kanazawa University Graduate School of Medicine
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- YONESHIMA Manabu
- Department of Gastroenterology, Municipal Tsuruga Hospital
Bibliographic Information
- Other Title
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- nilotinib内服加療中に小腸多発性GISTを発症した神経線維腫症1型の1例
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Abstract
A 60-year-old woman with neurofibromatosis type 1 presented to our hospital with melena. She reported a 1-year history of treatment with nilotinib hydrochloride hydrate for chronic myelogenous leukemia. Contrast-enhanced abdominal computed tomography revealed multiple intestinal tumors that were subsequently diagnosed as gastrointestinal stromal tumors (GIST) using single-balloon enteroscopy. Although the tumors showed no significant change over 1 year, partial jejunal resection was performed to confirm the diagnosis. Immunohistochemically, the tumors were GIST.
Journal
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- Nippon Shokakibyo Gakkai Zasshi
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Nippon Shokakibyo Gakkai Zasshi 111 (8), 1579-1586, 2014
The Japanese Society of Gastroenterology