- 【Updated on May 12, 2025】 Integration of CiNii Dissertations and CiNii Books into CiNii Research
- Trial version of CiNii Research Knowledge Graph Search feature is available on CiNii Labs
- Suspension and deletion of data provided by Nikkei BP
- Regarding the recording of “Research Data” and “Evidence Data”
Disappearance of a gastric lesion following modified FOLFOX6 chemotherapy in a patient with metastatic colorectal cancer: a case report and literature review
-
- IINO Chikara
- Department of Internal Medicine, Hirosaki City Hospital Department of Gastroenterology, Hirosaki University Graduate School of Medicine
-
- MIKAMI Tatsuya
- Department of Internal Medicine, Hirosaki City Hospital Division of Endoscopy, Hirosaki University Hospital
-
- SAWAYA Manabu
- Department of Internal Medicine, Hirosaki City Hospital Department of Gastroenterology, Hirosaki University Graduate School of Medicine
-
- YOSHIDA Kenta
- Department of Internal Medicine, Hirosaki City Hospital Department of Gastroenterology, Hirosaki University Graduate School of Medicine
-
- AIHARA Tomoyuki
- Department of Internal Medicine, Hirosaki City Hospital
-
- YAMAGATA Ryo
- Department of Internal Medicine, Hirosaki City Hospital
-
- SAKAMOTO Juichi
- Department of Internal Medicine, Hirosaki City Hospital
-
- TONO Hiroshi
- Department of Internal Medicine, Hirosaki City Hospital
-
- TANAKA Masanori
- Department of Pathology and Laboratory Medicine, Hirosaki City Hospital
-
- FUKUDA Shinsaku
- Department of Gastroenterology, Hirosaki University Graduate School of Medicine
Bibliographic Information
- Other Title
-
- 胃転移を有する大腸癌に対してmFOLFOX6療法により胃転移巣が内視鏡上消失した1例
Search this article
Description
A 48-year-old man with colorectal cancer and right inguinal lymph node metastasis had previously undergone radiotherapy and chemotherapy (uracil/tegafur/leucovorin) after a colostomy in another hospital before being referred to us. Esophagogastroduodenoscopy (EGD) revealed the presence of a gastric metastatic lesion. After three courses of treatment with a modified regimen of leucovorin plus 5-fluorouracil plus oxaliplatin-6 (mFOLFOX6), EGD revealed that the gastric lesion had disappeared; computed tomography revealed that the size of the primary tumor and inguinal lymph node metastasis were markedly reduced. Subsequently, he underwent rectal resection of the primary tumor and continued treatment with mFOLFOX6 in combination with bevacizumab. We reviewed 29 similar cases from the literature, and determined that surgical resection of the tumor and appropriate chemotherapy can lead to long-term survival for patients with gastric metastases from colorectal cancer. Furthermore, positive CK20 and CDX2 expression and negative CK7 expression were useful adjuncts in the immunohistochemical diagnosis of gastric metastases from colorectal adenocarcinoma.
Journal
-
- Nippon Shokakibyo Gakkai Zasshi
-
Nippon Shokakibyo Gakkai Zasshi 111 (10), 1983-1989, 2014
The Japanese Society of Gastroenterology
