書誌事項
- タイトル別名
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- Enhancement of Th1 Immune Response in Mice by the Ingestion of Suehirotake
- スエヒロタケ Schizophyllum commune Fries キンシタイ ノ ケイコウ セッシュ ニ ヨル マウス Th1 メンエキ オウトウ ゾウシン コウカ
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説明
The culture product of Suehirotake (Schizophyllum commune Fries) mycelium (SCP) is supposed to stimulate cellular immunity. In fact, Schizophyllan (β-1, 6-branched β-1, 3-glucan) contained in SCP has anti-tumor activity. In the present study, we investigated the effects of SCP feeding on cytokine production in mice in order to clarify the immunological effects of SCP as a dietary component. The levels of interleukin (IL)-12 and interferon (IFN)-γ produced in the culture supernatant of spleen cells from SCP-fed mice were significantly high compared to those in control group (P<0.05). Furthermore, the level of IFN-γ was dependent on the dose of SCP. The level of tumor necrosis factor (TNF)-α was not changed by SCP-feeding. These results suggest that SCP could be useful food with immunomodulating activities by promoting Th1 immune response via oral route.
収録刊行物
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- 日本食品科学工学会誌
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日本食品科学工学会誌 51 (2), 102-105, 2004
公益社団法人 日本食品科学工学会
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詳細情報 詳細情報について
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- CRID
- 1390001206408014080
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- NII論文ID
- 10012097559
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- NII書誌ID
- AN10467499
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- COI
- 1:CAS:528:DC%2BD2cXivVequ7o%3D
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- ISSN
- 18816681
- 1341027X
- http://id.crossref.org/issn/1341027X
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- NDL書誌ID
- 6855369
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDLサーチ
- Crossref
- CiNii Articles
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- 使用不可