書誌事項
- タイトル別名
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- Histopathology of spontaneous lesions in beagles used for toxicity studies.
- 毒性試験に使用したビーグル犬にみられた偶発病変の病理組織学〔英文〕
- ドクセイ シケン ニ シヨウシタ ビーグル イヌ ニ ミラレタ グウハツ ビョ
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抄録
A histopathological study was carried out on spontaneous subclinical lesions in 86 beagle dogs employed in toxicity studies. The lesions found in a young adult group were compared with those in an older age group. Lesions detected more frequently in the older age group included acidophilic crystalline intranuclear inclusions in the liver and kidney, cell infiltration in the submaxillary gland, a tubular fatty change and glomerular lipid deposition in the kidney, atrophy and cyst formation in the thymus, siderofibrotic nodules in the spleen, and parafollicular cell hyperplasia in the thyroid. Focal mesothelial proliferation in the epicardium of the heart, intranuclear inclusions in the epididymis, focal granulomatous inflammation in the kidney, and aberrant pancreas in the gallbladder were noted each in 1 case. Granulomas possibly caused by parasitic infection were found in 21 cases (24.4%).
収録刊行物
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- 日本獸醫學雜誌(The Japanese Journal of Veterinary Science)
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日本獸醫學雜誌(The Japanese Journal of Veterinary Science) 49 (1), 51-59, 1987
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206421404416
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- NII論文ID
- 110003917504
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- NII書誌ID
- AN00191788
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- COI
- 1:STN:280:BiiC1MblslI%3D
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- ISSN
- 18811442
- 00215295
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- NDL書誌ID
- 3123639
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- PubMed
- 3573492
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可