ニワトリの脾臓における胚中心形成細胞の微細構造

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タイトル別名
  • Fine structure of germinal center forming cells in chick spleen.
  • ニワトリの脾臓における胚中心形成細胞の微細構造〔英文〕
  • ニワトリ ノ ヒゾウ ニ オケル ハイチュウシン ケイセイ サイボウ ノ ビサ

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Ultrastructural changes of the cells forming germinal centers were examined in the chick spleen after intravenous injection of sheep red blood cells. The germinal center was formed by a cluster of large lymphoid cells and a septum of flattened reticular cells. The large lymphoid cell was characterized by numerous polysomes and a large euchromatic nucleus with a prominent nucleolus. In the developing germinal center the large lymphoid cells proliferated and became smaller in size. After the peak of development of the center they were gradually atrophied and finally became degenerative to exhibit pyknotic nuclei, condensed cytoplasm, some vacuoles and many cytoplasmic processes. From the formation of the germinal center through its degeneration, the transformation of lymphoid cells into plasma cells did not occur within the center. Plasma cells were appeared in the red pulp prior to the germinal center formation, and then they proliferated to aggregate around a periarterial lymphatic sheath.

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