Tumor-associated antigen detected by complement-dependent antibody cytotoxicity test and immunofluorescence test in enzootic bovine lymphosarcoma.
Bibliographic Information
- Other Title
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- 地方病性ウシ白血病における補体依存抗体細胞障害試験および免疫蛍光法によって検出された腫瘍関連抗原
- 地方病性ウシ白血病における補体依存抗体細胞障害試験および免疫蛍光法によって検出された腫瘍関連抗原〔英文〕
- チホウビョウセイ ウシ ハッケツビョウ ニ オケル ホタイ イゾン コウタイ
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Abstract
Tumor-associated antigens were studied on the neoplastic cells of cattle affected with bovine lymphosarcoma (BL) by complement-dependent antibody cytotoxicity (CDAC) test and immunofluorescence (IF) test using antiserum produced in rabbits which were immunized with tumors from four cows. The antiserum from rabbits was absorbed with erythrocytes and pooled cells of lymph nodes from normal cows. Neoplastic cells from 18 of 21 cases affected with enzootic BL (EBL) showed cytotoxic reaction by CDAC test, but those were negative from one case of calf type BL (CBL). Cytoplasmic antigen was detected by IF test in acetone-fixed neoplastic cells from all 52 EBL cows examined. No reaction was observed in lymphocytes of normal 9 cows and 3 fetuses from EBL cows as well as in neoplastic cells of 3 CBL calves. Fluorescence was observed in 37% to 97% of peripheral blood lymphocytes (PBL) from all EBL cases examined. None of PBL from 7 normal cows showed positive reaction.
Journal
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- The Japanese Journal of Veterinary Science
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The Japanese Journal of Veterinary Science 45 (2), 195-202, 1983
JAPANESE SOCIETY OF VETERINARY SCIENCE
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Keywords
Details 詳細情報について
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- CRID
- 1390001206421628032
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- NII Article ID
- 110003947809
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- NII Book ID
- AN00191788
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- COI
- 1:STN:280:DyaL2c%2Fjslaiuw%3D%3D
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- ISSN
- 18811442
- 00215295
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- NDL BIB ID
- 2590052
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- PubMed
- 6355592
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- Text Lang
- en
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed