Experimental infection of bovine leukemia virus in small laboratory animals.
Bibliographic Information
- Other Title
-
- 実験小動物を用いた牛白血病ウイルスの感染実験
- 実験小動物を用いた牛白血病ウイルスの感染実験〔英文〕
- ジッケン ショウドウブツ オ モチイタ ウシ ハッケツビョウ ウイルス ノ カ
Search this article
Description
Small laboratory animals were experimentally inoculated with bovine leukemia virus (BLV). Antibodies against BLV were detected in rabbits and guinea pigs. In the rabbits inoculated with leukocytes from a BLV-infected cow, the antibody titers against BLV glycoprotein (gp) increased within 2 months after inoculation and persisted for more than 7 months in the range between 2 and 128. Infective BLV was not detected in peripheral blood leukocytes from these animals by the syncytium induction assay. However, sheep and rabbits inoculated with leukocytes or blood from BLV-antibody positive rabbits, developed gp antibodies against BLV. These results show that rabbits are susceptible to BLV but not as sensitive as cattle and sheep. However, the rabbit would be applicable as an experimental animal for the study of enzootic bovine leukosis.
Journal
-
- The Japanese Journal of Veterinary Science
-
The Japanese Journal of Veterinary Science 50 (6), 1245-1251, 1988
JAPANESE SOCIETY OF VETERINARY SCIENCE
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390001206423090816
-
- NII Article ID
- 110003917909
-
- NII Book ID
- AN00191788
-
- COI
- 1:STN:280:DyaL1M3js12jtg%3D%3D
-
- ISSN
- 18811442
- 00215295
-
- NDL BIB ID
- 3211724
-
- PubMed
- 2854587
-
- Text Lang
- en
-
- Data Source
-
- JaLC
- IRDB
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- Abstract License Flag
- Disallowed