Regulation of hexose transport in animal cells.

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  • YAMADA Kazuo
    Department of Biochemistry, Hiroshima University, School of Medicine Laboratry of Active Transport, National Institute for Physiological Sciences

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Other Title
  • 動物細胞における糖輸送の調節
  • ドウブツ サイボウ ニ オケル トウ ユソウ ノ チョウセツ

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Abstract

Simple diffusion, sodium-dependent (active) and-independent (facilitated) transports are generally involved in hexose transport in animal cells. The regulation of facilitated hexose transport has been briefly reviewed. Hexose transport regulation is observed in most cells where the rate of hexose trans-fer is rate limiting for hexose metabolism. Experimental methods used for assay of transport activities and indentification of glucose carrier are very important to deduce any definitive conclusion regarding the regulation of glucose transport. Possible mechanisms of transport regulation might involve 1) control of the carrier synthesis and/or turn over 2) recycling of the carrier 3) modification of the carrier 4) interaction between the carrier and its lipid environment.

Journal

  • MEMBRANE

    MEMBRANE 12 (6), 313-322, 1987

    THE MEMBRANE SOCIETY OF JAPAN

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