ラットアレルギー性喘息モデルに対するM-711の効果

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  • Effect of M-711 on Experimental Asthma in Rats.
  • Effect of M-711 on experimental asthma

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We experimentally demonstrated the anti-asthmatic effects of M-711, the dry extract of a Chinese herb medicine called Moku-boi-to, using the rat model of allergic asthma. Allergic asthma was induced by the antigen-antibody reaction in the rats and they showed anaphylactic symptoms accompanied with hypotension and depression of respiratory function. More than 20 mg/kg body weight of M-711 was effective in relieving the asthmatic symptoms like methylephedrine. It could lessened the suppress of respiration and provided a good improvement. It also reduced a drop of the blood pressure and improved it quickly. Its ingredients alone were much less effective than M-711 as the total. Those data suggested that M-711 was effective for alleviating allergic asthma in the present study and that its action was provided by interaction of all ingredient raw herbs of M-711.

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