書誌事項
- タイトル別名
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- Effect of Extracellular Matrix on Two Cell Lines Established from Mongolian Gerbil's (Meriones unguiculatus) Malignant Melanoma.
- スナネズミ悪性黒色腫から樹立された2つの細胞培養系に対する細胞外マトリクスの影響〔英文〕
- スナネズミ アクセイ コクショクシュ カラ ジュリツサレタ 2ツ ノ サイボウ
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We investigated the effect of extracellular matrix (ECM) on the adhesion, morphology and proliferation of two Mongolian gerbil's melanoma cell lines (MGM-S, MGM-A) which differed in malignancy. Fibronectin matrix was detected on the cell surface of MGM-S by immunofluorescence techniques. MGM-A cells, showing a multipolar shape, were widely spread over the dishes coated with fibronectin, laminin or type IV collagen. The adhesion rate of MGM-A cells to ECM components was higher compared to that in controls. Attachment to laminin was conspicuously promoted. The effect of laminin on MGM-A cell growth was also the highest among the substrates examined. On the other hand, these ECM components did not affect MGM-S cells. These results suggest that laminin and fibronectin may participate in the malignancy of MGM cell lines.
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 57 (4), 635-640, 1995
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206424490624
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- NII論文ID
- 130003572140
- 110003916340
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- NII書誌ID
- AA10796138
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 3631148
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- PubMed
- 8519890
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可