ネコ及びイヌに人工寄生させたネコノミに対するlufenuron経口投与の駆除効果

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タイトル別名
  • Disinfestation of Experimentally Infested Cat Fleas, Ctenocephalides felis, on Cats and Dogs by Oral Lufenuron.
  • ネコ及びイヌに人工寄生させたネコノミに対するlufenuron経口投与の駆除効果〔英文〕
  • ネコ オヨビ イヌ ニ ジンコウ キセイサセタ ネコノミ ニ タイスル luf

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In vivo efficacy of orally administered lufenuron, an insect growth regulator, in disinfesting cat fleas was evaluated, using flea-free cats and dogs which were purchased and infested every 10 days with cat fleas from a colony kept in our laboratory. Lufenuron was orally administered as a single dose of 15, 30, or 60 mg/kg to cats, and 5, 10 or 20 mg/kg to dogs. In cats, adult flea emergence was intensively prevented for 30 days by dosing of 15 mg/kg of lufenuron and 40 days by 30 or 60 mg/kg. The average egg hatch rate in 15mg/kg group was, however, significantly higher than those in 30 mg/kg or more, suggesting necessity to dose 30 mg/kg to cats to prevent development of cat fleas effectively. In dogs, a lower dose of the drug, 10 mg/kg seemed to be sufficient for the complete prevention of flea development.

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