Polymeric N-Acetyl-D-Glucosamine (Chitin) Induces Prostaglandin E2 in Dogs.

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  • ポリN-アセチル-D-グルコサミン(キチン)は犬においてプロスタダランディンE<SUB>2</SUB>(PGE<SUB>2</SUB>)を誘導する

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The level of prostaglandin E2 (PGE2) in the exudate induced by subcutaneous implantation of a complex formed from non-woven fabric of polyester (NWF) and polymeric N-acety1-D-glucosamine (chitin) (chitin/NWF) or by implantation of NWF in dogs was measured by radioimmunoassay. The amount of PGE2 in the exudate induced by chitin/NWF was about five times as high as that in the exudate induced by NWF (p<0.05), while the level of PGE2 in the exudate was similar to that ip serum.

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