Prevalence of Circulating Antibodies to p10, a Non-structural Protein of the Borna Disease Virus in Cats with Ataxia.
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- OUCHI Atsuo
- Tsukuba Central Laboratories, Kyoritsu Seiyaku Corporation
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- KISHI Masahiko
- Tsukuba Central Laboratories, Kyoritsu Seiyaku Corporation
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- KOBAYASHI Takeshi
- Research Institute for Microbial Diseases, Osaka University
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- LAI Patrick K.
- Department of Biosciences, Salem International University
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- MALIK Tahir H.
- Department of Biosciences, Salem International University
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- IKUTA Kazuyoshi
- Research Institute for Microbial Diseases, Osaka University
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- MOCHIZUKI Masami
- Laboratory of Clinical Microbiology, Kyoritsu Seiyaku Corporation
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抄録
Japanese domestic cats were surveyed for circulating antibodies to the p10 and p24 proteins of the Borna disease virus (BDV) by Western blotting. Twenty-four of 52 cats (46.2%) with ataxia and other neurologic symptoms of unknown cause were positive for antibodies to BDV p10 and/or p24. In contrast, cats without neurological symptoms gave a significantly lower prevalence of anti-BDV antibodies to p10 and/or p24 (36 of 152 cats, 23.7%). Thirty specific pathogen-free (SPF) cats tested as controls were uniformly negative to BDV p10 and p24 antigens. These results suggest that BDV may play a role in ataxia in cats. Additionally, our results suggest that it is necessary to use both p10 and p24 as antigens to detect circulating antibodies to BDV in cats.
収録刊行物
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- Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ
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Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ 63 (12), 1279-1285, 2001
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206425714304
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- NII論文ID
- 110003920790
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- NII書誌ID
- AA10796138
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- COI
- 1:CAS:528:DC%2BD38XlvFGisw%3D%3D
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 6016847
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- PubMed
- 11789604
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可