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- KAGEYAMA Soichi
- Hokkaido Animal Research Center
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- HIRAYAMA Hiroki
- Hokkaido Animal Research Center
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- MORIYASU Satoru
- Hokkaido Animal Research Center
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- INABA Mutsumi
- Laboratory of Molecular Medicine, Graduate School of Veterinary Medicine, Hokkaido University
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- ITO Daisuke
- Laboratory of Molecular Medicine, Graduate School of Veterinary Medicine, Hokkaido University
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- OHTA Hiroshi
- Laboratory of Molecular Medicine, Graduate School of Veterinary Medicine, Hokkaido University
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- SAWAI Ken
- Hokkaido Animal Research Center
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- MINAMIHASHI Akira
- Hokkaido Animal Research Center
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- ONOE Sadao
- Hokkaido Animal Research Center
書誌事項
- タイトル別名
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- Genetic Diagnosis of Band 3 Deficiency and Sexing in Bovine Preimplantation Embryos
この論文をさがす
説明
Band 3 deficiency with hereditary spherocytosis and hemolytic anemia in Japanese black cattle, band 3Bov.Yamagata, is caused by a total lack of band 3 protein with an autosomal dominant inheritance. Genotyping for band 3 deficiency and sexing were successfully achieved in biopsied embryo cells with efficiencies of 98.4% and 97.4%, respectively. Transfer of the embryo that was determined as homozygous for the mutant allele into a recipient cow resulted in the production of a fetus exhibiting the genotype and red cell phenotypes characteristic of band 3Bov.Yamagata. These results demonstrate that our procedure is reliable and applicable to produce animals free from or homozygous for the mutant allele by breeding carrier animals.<br>
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 68 (4), 319-323, 2006
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206425745152
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- NII論文ID
- 110004758083
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- NII書誌ID
- AA10796138
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 7942667
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可