後天性重症筋無力症罹患犬にみられた胸腺腫および多発性胸腺嚢胞

DOI 機関リポジトリ 機関リポジトリ (HANDLE) Web Site Web Site ほか1件をすべて表示 一部だけ表示 被引用文献3件 参考文献36件 オープンアクセス
  • UCHIDA Kazuyuki
    Department of Veterinary Pathology, Faculty of Agriculture, Miyazaki University
  • AWAMURA Yuichi
    Totsuka-Animal Hospital
  • NAKAMURA Tomoko
    Department of Veterinary Pathology, Faculty of Agriculture, Miyazaki University
  • YAMAGUCHI Ryoji
    Department of Veterinary Pathology, Faculty of Agriculture, Miyazaki University
  • TATEYAMA Susumu
    Department of Veterinary Pathology, Faculty of Agriculture, Miyazaki University

書誌事項

タイトル別名
  • Thymoma and Multiple Thymic Cysts in a Dog with Acquired Myasthenia Gravis.

この論文をさがす

説明

An anterior mediastinal cystic lesion in an 11-year-old mongrel dog was examined. The dog showed dysbasia and vomiting due to megaoesophagus, and anterior mediastinal round mass lesion, approximately 35 mm in diameter, was found by X ray. Based on clinical examinations, the dog was diagnosed as acquired myasthenia gravis and was successfully controlled by anticholinesterase treatment for approximately 4 months. The dog died of thermic stroke and was necropsied. Grossly, fatty tissues with cysts containing yellowish fluid and white nodules were found in the anterior mediastinal area. Histopathologically, multiple cysts, neoplastic tissues, and atrophic thymus were found within the examined tissues. The cysts were lined by thin wall consisting of ciliated long cuboidal and non-ciliated round cells and were filled with eosinophilic colloidal fluid. Some extended cysts contained neoplastic foci within their lumen and walls. The neoplastic tissues consisted of mixed population of large epithelial cells with abundant clear cytoplasm and large oval nuclei, and lymphocytes. Immunohistochemically, proliferating epithelial cells were intensely positive for keratin and cytokeratin, and more than half number of infiltrating lymphocytes were intensely positive for CD3 suggesting T cells. All these findings indicate the neoplastic lesion is thymoma and multiple cysts are considered as thymic or brachial cleft cysts.

収録刊行物

被引用文献 (3)*注記

もっと見る

参考文献 (36)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ