A Case of Intracytoplasmic Edema of Follicular Epithelial Cells in Rat Thyroid.

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  • ラット甲状腺濾胞上皮細胞に観察された細胞質内水腫の1例(短報)
  • ラット甲状腺濾胞上皮細胞に観察された細胞質内水腫の1例〔英文〕
  • ラット コウジョウセン ロホウ ジョウヒ サイボウ ニ カンサツサレタ サイボ

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Abstract

Hydropic change of follicular epithelial cells in the thyroid was observed in a female Fischer 344 rat. Microscopically follicular epithelial cells were characterized by edematous swelling with weakly eosinophilic and homogeneous cytoplasm. The cytoplasm was negative for periodic acid-Schiff reaction, and thyroxine- and thyroglobulin-immunohistochemical reactions. Electron-microscopically, a small amount of amorphous substance was noted in remarkably dilated rough-surfaced endoplasmic reticulum (r-ER), and slight regressive changes of cytoplasmic organella were also observed. These morphological changes may indicate that focal intracytoplasmic edema was occurred in r-ER, and that the change belonged to hydropic degeneration of the thyroid follicular cells in the thyroid.

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