Experimental Study of Materials for Patch Graft on Right Ventricular Outflow Tract under Extracorporeal Circulation in Dogs. Comparison between Denacol EX-313-Treated Bovine Jugular Vein Graft and Expanded Polytetrafluoroethylene(EPTFE) Graft.

DOI Web Site Web Site PubMed 被引用文献7件 参考文献33件
  • MATSUMOTO Hideki
    Animal Clinical Research Foundation
  • SUGIYAMA Shino
    Department of Veterinary Surgery, Faculty of Agriculture, Tokyo University of Agriculture and Technology
  • SHIBAZAKI Akira
    Department of Veterinary Surgery, Faculty of Agriculture, Tokyo University of Agriculture and Technology
  • TANAKA Ryou
    Department of Veterinary Surgery, Faculty of Agriculture, Tokyo University of Agriculture and Technology
  • TAKASHIMA Kazuaki
    Animal Clinical Research Foundation
  • NOISHIKI Yasuharu
    First Department of Surgery, Yokohama City University School of Medicine
  • YAMANE Yoshihisa
    Department of Veterinary Surgery, Faculty of Agriculture, Tokyo University of Agriculture and Technology

この論文をさがす

抄録

A comparison between a bovine jugular vein treated with a hydrophilic polyepoxy compound cross-linker (Denacol), and expanded polytetrafluoroethylene (EPTFE), an artificial material, as a patch graft for the reconstruction of the right ventricular outflow tract under extracorporeal circulation in dogs, as if they had pulmonic stenosis, was made. Hemodynamic and histological examinations were conducted two weeks after the transplantation. Hemodynamic problems were not observed in either the Denacol or EPTFE groups. Macroscopically, organization of new tissue on the graft surface was more marked in the EPTFE group than in the Denacol group, and newly-formed tissue was seen surrounding the border of the graft and burying it in the EPTFE group. In the Denacol group, microscopic findings revealed the presence of inflammatory cells and fibroblasts, and an invasion of the graft by collagen fibers and elastic fibers. In the EPTFE group, there was minimal cellular infiltration of the graft and a thick layer consisting of collagen fibers and fibroblasts was observed around the graft. These results indicated that two weeks after transplantation the graft was better assimilated and organized with blood vasculature in the patch graft in the Denacol group than in the EPTFE group.

収録刊行物

被引用文献 (7)*注記

もっと見る

参考文献 (33)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ