Molecular Epidemiological Investigation of Foot-and-Mouth Disease Virus in Korea in 2000.
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- SHIN Jin-Ho
- National Veterinary Research and Quarantine Service
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- SOHN Hyun-Joo
- National Veterinary Research and Quarantine Service
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- CHOI Kang-Seuk
- National Veterinary Research and Quarantine Service
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- KWON Byung-Jun
- National Veterinary Research and Quarantine Service
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- KO Young-Joon
- National Veterinary Research and Quarantine Service
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- AN Dong-Jun
- National Veterinary Research and Quarantine Service
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- CHA Sang-Ho
- National Veterinary Research and Quarantine Service
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- PARK Jong-Hyeon
- National Veterinary Research and Quarantine Service
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- JEONG Woo-Seog
- National Veterinary Research and Quarantine Service
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- PARK Jee-Yong
- National Veterinary Research and Quarantine Service
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- CHOI Cheong-Up
- National Veterinary Research and Quarantine Service
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- KWEON Chang-Hee
- National Veterinary Research and Quarantine Service
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- SONG Jae-Young
- National Veterinary Research and Quarantine Service
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- KIM Jong-Yeom
- National Veterinary Research and Quarantine Service
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- AN Soo-Hwan
- National Veterinary Research and Quarantine Service
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- KIM Soon-Jae
- College of Veterinary Medicine, Konkuk University
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- JOO Yi-Seok
- National Veterinary Research and Quarantine Service
この論文をさがす
抄録
The genetic relatedness of 7 Korean type O field strains of foot-and-mouth disease virus (FMDV) in clinical specimens collected from 5 different geographic locations in 2000 was investigated. The sequence of 162 nucleotides (nt 478-639) at the 3' end of the 1D (VP1) genes was determined from amplified cDNA fragments, and subjected to the analysis for the sequence identity/divergence and phylogenetic relationship. The overall nucleotide sequence divergence among the 7 field strains was 0 to 3.8%, suggesting that they are closely related to each other. Phylogenetic analysis with the known Middle East-South Asia (ME-SA) topotype strains showed that the 7 Korean field strains formed two distinct clusters within the same lineage of the ME-SA topotype strains. Cluster 1 consisted of the strains of the primary foci of infection (Paju and Hongseong), and closely related to the strains prevailed in the Far East. Cluster 2 comprised those of subsequently affected regions (Boryeong, Yongin, and Chungju), and was further diverged from the Cluster 1. The result of phylogenetic analysis indicated that the Korean strains may have evolved from a common ancestor of the Pan Asia strains, and that at least 2 phylogenetically clustered variants within the same lineage were prevalent during the epidemic. The potential origin and sources of the virus introduction to Korea were discussed.<br>
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 65 (1), 9-16, 2003
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206426785792
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- NII論文ID
- 110003886096
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- NII書誌ID
- AA10796138
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- COI
- 1:STN:280:DC%2BD3s%2Fms1GntA%3D%3D
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 6444362
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- PubMed
- 12576698
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可