馬におけるミダゾラム-ケタミン-メデトミジン混合液持続点滴麻酔とセボフルラン麻酔の併用による麻酔効果および心血管系への影響
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- KUSHIRO Tokiko
- Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University
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- YAMASHITA Kazuto
- Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University
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- UMAR Mohammed Ahmed
- Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University
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- MAEHARA Seiya
- Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University
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- WAKAIKI Shinsuke
- Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University
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- ABE Reona
- Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University
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- SENO Takahiro
- Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University
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- TSUZUKI Keiko
- Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University
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- IZUMISAWA Yasuharu
- Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University
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- MUIR William W.
- Department of Veterinary Clinical Sciences, School of Veterinary Medicine, The Ohio State University
書誌事項
- タイトル別名
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- Anesthetic and Cardiovascular Effects of Balanced Anesthesia Using Constant Rate Infusion of Midazolam-Ketamine-Medetomidine with Inhalation of Oxygen-Sevoflurane (MKM-OS Anesthesia) in Horses
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説明
The anesthetic sparring and cardiovascular effects produced by midazolam 0.8 mg/ml-ketamine 40 mg/ml-medetomidine 0.05 mg/ml (0.025 ml/kg/hr) drug infusion during sevoflurane in oxygen (MKM-OS) anesthesia was determined in healthy horses. The anesthetic sparring effects of MKM-OS were assessed in 6 healthy thoroughbred horses in which the right carotid artery was surgically relocated to a subcutaneous position. All horses were intubated and ventilated with oxygen using intermittent positive pressure ventilation (IPPV). The end-tidal concentration of sevoflurane (ETSEV) required to maintain surgical anesthesia was approximately 1.7%. Heart rate and mean arterial blood pressure averaged 23-41 beats/min and 70-112 mmHg, respectively. All horses stood between 23-44 min after the cessation of all anesthetic drugs. The cardiovascular effects of MKM-OS anesthesia were evaluated in 5 healthy thoroughbred horses ventilated using IPPV. Anesthesia was maintained for 4 hr at an ETSEV of 1.7%. Each horse was studied during left lateral (LR) and dorsal recumbency (DR) with a minimum interval between evaluations of 1 month. Cardiac output and cardiac index were maintained between 70-80% of baseline values during LR and 65-70% of baseline values during DR. Stroke volume was maintained between 75-85% of baseline values during LR and 60-70% of baseline values during DR. Systemic vascular resistance was not different from baseline values regardless of position. MKM-OS anesthesia may be useful for prolonged equine surgery because of its minimal cardiovascular depression in both of lateral and dorsal recumbency.<br>
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 67 (4), 379-384, 2005
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206427007360
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- NII論文ID
- 110003963738
- 130000448321
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- NII書誌ID
- AA10796138
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 7341852
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- PubMed
- 15876787
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可