Tick-encoded serine proteinase inhibitors(Serpins): potencial target antigens for tick vaccine development
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- MULENGA Albert
- Graduate School of Veterinary Medicine, Hokkaido University
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- SUGINO Maiko
- Graduate School of Veterinary Medicine, Hokkaido University
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- NAKAJIMA Mie
- Graduate School of Veterinary Medicine, Hokkaido University
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- SUGIMOTO Chihiro
- Graduate School of Veterinary Medicine, Hokkaido University The National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine
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- ONUMA Misao
- Graduate School of Veterinary Medicine, Hokkaido University
書誌事項
- タイトル別名
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- Tick-Encoded Serine Proteinase Inhibitors (Serpins); Potential Target Antigens for Tick Vaccine Development.
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説明
Immunological protection of hosts against tick infestation is at present the most practically sustainable alternative tick control method to the current use of acaricides that is riddled with serious limitations. The current focus of tick vaccine research is the identification, cloning and in vitro production of recombinant tick vaccine candidate antigens. We have examined a selected number of reports on the roles of parasite-encoded members of the serine proteinase inhibitor (serpin) superfamily in modulation of mammalian anti-parasite defense and developed some food for thought commentaries on the possibility of targeting this class of proteins for anti-tick vaccine development.
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 63 (10), 1063-1069, 2001
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206427067136
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- NII論文ID
- 130000449736
- 110003920749
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- NII書誌ID
- AA10796138
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- COI
- 1:CAS:528:DC%2BD3MXptVertrs%3D
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 5953661
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- PubMed
- 11714020
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可