Studies on Feline Panleukopenia : II. Antigenicities of the Virus

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  • 猫汎白血球減少症に関する研究 : II. ウイルスの各種抗原性
  • ネコ ハン ハッケッキュウ ゲンショウショウ ニカンスルケンキュウ 2 ウイル

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Abstract

Infectivity, hemagglutination (HA) activity and complement-fixation (CF) activity of feline parvovirus (FPV) were investigated with 11 strains of the virus. The peaks of infectivity, HA activity and CF activity were observed similarly at a buoyant density of 1.32-1.35 g/ml in CsCl gradient. The eleven strains of FPV had the same CF antigenicity and were not distinguished from one another. Both infectivity and HA activity were affected with potassium periodate (KIO4) and formaldehyde. Since a receptor for viral hemagglutinin on the porcine erythrocyte was inactivated almost completely by trypsin, KIO4 and α-amylase, and to some extent by formaldehyde, it was supposed to have the same character as a glycoprotein. The agglutinability of erythrocytes by the virus was reduced when treated with neuraminidase as well.

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