Possible Role of Insulin-Like Factor 3 in the Bovine Corpus Luteum
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- ABE Misato
- Laboratory of Reproductive Endocrinology, Graduate School of Natural Science and Technology, Okayama University, Okayama 700–8530, Japan
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- HOJO Takuo
- Laboratory of Reproductive Endocrinology, Graduate School of Natural Science and Technology, Okayama University, Okayama 700–8530, Japan
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- KOZAI Keisuke
- Laboratory of Reproductive Physiology, Graduate School of Environmental and Life Science, Okayama University, Okayama 700–8530, Japan
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- OKUDA Kiyoshi
- Laboratory of Reproductive Endocrinology, Graduate School of Natural Science and Technology, Okayama University, Okayama 700–8530, Japan Laboratory of Reproductive Physiology, Graduate School of Environmental and Life Science, Okayama University, Okayama 700–8530, Japan
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抄録
Insulin-like factor 3 (INSL3) is a local regulator in mammalian gonads, but little is known of its function in bovine corpus luteum (CL). Here, we show that RXFP2 protein, the receptor of INSL3, was expressed throughout the estrous cycle and significantly high at the early luteal stage compared to the regressed luteal stage. INSL3 stimulated progesterone secretion, but not prostaglandin F2α and viability in cultured luteal cells. Together, these results suggest that INSL3 plays a luteotropic role as a local regulator in the bovine CL.
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 75 (5), 629-632, 2013
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206427817216
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- NII論文ID
- 130002502166
- 40019693738
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- NII書誌ID
- AA10796138
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- COI
- 1:STN:280:DC%2BC3s7pslKjsw%3D%3D
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 024676321
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- PubMed
- 23220928
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 使用不可