Anatomy: Reproductive performance in diabetes mice with a special reference to uterine natural killer cells and placental growth factor

  • PHICHITRASILP Thanmaporn
    The United Graduate School of Veterinary Science, Yamaguchi University
  • HONDO Eiichi
    The United Graduate School of Veterinary Science, Yamaguchi University Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University
  • RERKAMNUAYCHOKE Worawut
    Department of Veterinary Anatomy, Kasetsart University
  • WAKITANI Shoichi
    The United Graduate School of Veterinary Science, Yamaguchi University
  • SUGIYAMA Makoto
    Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University
  • TERAKAWA Jumpei
    Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University
  • KISO Yasuo
    The United Graduate School of Veterinary Science, Yamaguchi University Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University

書誌事項

タイトル別名
  • Reproductive Performance in Diabetes Mice with a Special Reference to Uterine Natural Killer Cells and Placental Growth Factor

この論文をさがす

抄録

To determine the effect of diabetes on reproductive performance, two kinds of diabetes mice, i.e., KK/TaJcl mice with Type-II diabetes and Streptozotocin-induced diabetes mice with Type-I diabetes, were used in this study. Particular attention was paid to uterine natural killer (uNK) cells and placental growth factor (PlGF). The number of fetuses, the fetal and placental weights in both diabetes mice were significantly decreased when compared to controls. Surprisingly, uNK cells in both diabetes mice persisted in the metrial gland even at the term of pregnancy. Although PlGF expression in both diabetes mice was significantly decreased, PlGF protein did not change. These results show that diabetes condition affects reproductive performance, particularly uNK cell behavior, but not PlGF production.<br>

収録刊行物

参考文献 (21)*注記

もっと見る

関連プロジェクト

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ