Pathology: A case of canine vasotropic and vasoinvasive nonepitheliotropic lymphoma with unusual tumor cells and extensive dermal necrosis
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- YASUNO Kyohei
- Research Institute of Biosciences, Azabu University
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- SATO Masafumi
- Kariya Animal Hospital
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- KARIYA Kazuhiro
- Kariya Animal Hospital
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- OGIHARA Kikumi
- Laboratory of Environmental Pathology, Azabu University
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- SHIROTA Kinji
- Research Institute of Biosciences, Azabu University Laboratory of Veterinary Pathology, Azabu University
書誌事項
- タイトル別名
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- A Case of Canine Vasotropic and Vasoinvasive Nonepitheliotropic Lymphoma with Unusual Tumor Cells and Extensive Dermal Necrosis
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説明
A 14-year-old, spayed female Shih-tzu dog presented with masses in the dorsal aspect of cervical region and digit of the right anterior limb. Extensive necrosis was seen in the dermal tissue overlying the tumor, and diffuse round cell proliferation and infiltration were seen histologically from the superficial dermis to the deep dermis. Two types of proliferating cells were present: lymphoblast-like cells with round-oval, vesicular nuclei and moderate-large nucleoli; and smaller cells with characteristic irregularly shaped nuclei. Electron microscopy of these smaller cells showed cerebriform, pleomorphic nuclei with a chromatin pattern characteristic of lymphoid cells, as seen in lymphoblast-like tumor cells. Immunohistochemically, both types of tumor cells were positive for CD3. Most vessel walls had been invaded by tumor cells, resulting in extensive dermal necrosis and hemorrhage. Based on these histopathological findings, the tumor was diagnosed as vasotropic and vasoinvasive nonepitheliotropic lymphoma, characterized by a notable presence of unusual tumor cells with irregularly shaped nuclei and extensive dermal necrosis.<br>
収録刊行物
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- The Journal of Veterinary Medical Science
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The Journal of Veterinary Medical Science 71 (1), 109-112, 2009
公益社団法人 日本獣医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206430446080
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- NII論文ID
- 110007055387
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- NII書誌ID
- AA10796138
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- ISSN
- 13477439
- 09167250
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- NDL書誌ID
- 9796584
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- PubMed
- 19194086
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDLサーチ
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