Efficacy of Mediastinoscopy for the Diagnosis of Small Cell Lung Cancer: A Case Report

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  • Endo Daisuke
    Department of Respiratory Medicine, Yokosuka Municipal Hospital
  • Onose Akira
    Department of Respiratory Medicine, Yokosuka Municipal Hospital
  • Ono Minako
    Department of Respiratory Medicine, Yokosuka Municipal Hospital
  • Ishibashi Naoya
    Department of Radiology, Yokosuka Municipal Hospital
  • Sato Yoshihiro
    Department of Respiratory Medicine, Yokosuka Municipal Hospital
  • Hiranuma Hisato
    Department of Respiratory Medicine, Yokosuka Municipal Hospital
  • Nagaoka Kenichi
    Department of Respiratory Medicine, Yokosuka Municipal Hospital
  • Akahoshi Toshiki
    Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine
  • Gon Yasuhiro
    Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine
  • Hachisuka Hisayoshi
    Department of Respiratory Medicine, Yokosuka Municipal Hospital
  • Hashimoto Shu
    Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine

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Other Title
  • 縦隔鏡によって診断した肺小細胞癌の一例
  • 症例報告 縦隔鏡によって診断した肺小細胞癌の一例
  • ショウレイ ホウコク ジュウカクキョウ ニ ヨッテ シンダン シタ ハイ ショウサイボウガン ノ イチレイ

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Abstract

We report a case of small cell lung cancer with metastasis without any lesion in the lungs. The patient was 55-year-old man who visited to the hospital with dizziness. He underwent general examinations and enhanced-magnetic resonance imaging (MRI) of the head revealed that a lesion with ring enhancement sign in the cerebellum. Despite the fact that no lesions were detected in his lungs in chest computed tomography (CT), mediastinal lymph node enlargement and elevated levels of ProGRP in serum indicated an unknown primary small cell lung cancer and its brain metastasis. A biopsy of No. 3 lymph node performed by mediastinoscopy revealed small-cell lung cancer (SCLC). The patient was treated with chemotherapy after the diagnosis, and although the treatment was effective temporarily, the patient died 18 months after the diagnosis.

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