Clinical studies of myocardial computer scintigraphy with 131I-MAA injected directly into the coronary artery

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  • CLINICAL STUDIES OF MYOCARDIAL COMPUTER SCINTIGRAPHY WITH <SUP>131</SUP>I-MAA INJECTED DIRECTLY INTO THE CORONARY ARTERY

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A total of 20 patients with suspected coronary artery disease received intracoronary injection of 131I-MAA, as the safety of this method was confirmed by animal experiments. The radio-nuclide images of the myocardium obtained with scintillation camera were stored on 1600 word memory and transferred to a computer-compatible magnetic tape recorder. The quality of the images were improved by computer processing, i.e. "nine-point" smoothing and iterative approximation. Myocardial computer scintigrams by this data processing clearly visualized the distribution of the coronary blood flow and made it easy to demonstrate ischemic myocardium. From our experiences, we concluded that 131I-MAA myocardial scintigraphy combined with coronary angiography would certainly provide much more informations concerning the diagnosis and management of ischemic heart disease .

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