Developement of substrains in spontaneously hypertensive rats Genealogy,isozymes and effect of hypercholesterolemic diet
書誌事項
- タイトル別名
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- DEVELOPMENT OF SUBSTRAINS IN SPONTANEOUSLY HYPERTENSIVE RATS: GENEALOGY, ISOZYMES AND EFFECT OF HYPERCHOLESTEROLEMIC DIET
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説明
Genealogical study and experimental fat-cholesterol and salt loadings showed that the present strain (F26-27) of spontaneously hypertensive rats consisted of several substrains with no difference in the level of blood pressure but with a marked difference in the incidence of cardiovascular lesions. Biochemical specificities of these substrains were demonstrated by ALPase and esterase isozymes in the liver and serum. Different responses in serum cholesterol level to the hypercholesterolemic diet served as a further differentiation of some lines among these substrains and were seemingly related to their vulnerability to cardiovascular lesions under these experimental conditions.
収録刊行物
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- JAPANESE CIRCULATION JOURNAL
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JAPANESE CIRCULATION JOURNAL 36 (5), 461-470, 1972
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390001206432893184
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- NII論文ID
- 130003420159
- 110002601709
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- NII書誌ID
- AN00191970
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- COI
- 1:CAS:528:DyaE3sXltVeqtLk%3D
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- ISSN
- 13474839
- 00471828
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- NDL書誌ID
- 7616807
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- PubMed
- 5068728
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- NDLサーチ
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可