Aggressive fibromatosis of the mandibular region: A report of an infant case

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  • TAKAHASHI Yoshihiro
    Department of Dentistry and Oral-Maxillo-Facial Surgery, Faculty of Medicine, Oita University
  • KONO Tatsuyuki
    Department of Dentistry and Oral-Maxillo-Facial Surgery, Faculty of Medicine, Oita University
  • ONO Keiichiro
    Department of Dentistry and Oral-Maxillo-Facial Surgery, Faculty of Medicine, Oita University
  • KAWANO Kenji
    Department of Dentistry and Oral-Maxillo-Facial Surgery, Faculty of Medicine, Oita University

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Other Title
  • 幼児の下顎部に生じた侵襲性線維腫症の1例
  • ヨウジ ノ カガクブ ニ ショウジタ シンシュウセイ センイ シュショウ ノ 1レイ

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Abstract

A case of aggressive fibromatosis of a 29-month-old girl is presented. Her mother noticed swelling in the right mandibular region about two months before her first visit to our hospital. At the first visit, the intraoral examination revealed a mass in the vestibule of the right lower molar region. The lesion was elastic-soft in consistency and showed slight tenderness. The covering mucosa was intact. Under a tentative diagnosis of lymphangioma, the lesion had grown rapidly at the follow-up. CT scan revealed a well-demarcated mass with a resorption of the mandibular bone, and the root of right lower D was affected by the lesion. On MRI, the lesion was of low intensity in the T1 enhanced image and of medium intensity in the T2, without intensity regression on the fat-regression T2 image. A biopsy specimen showed the proliferation of spindle-shaped cells with an interlacing bundle pattern and the appearance of hyalinized collagen fibers. The pathological findings were suggestive of aggressive fibromatosis. She underwent excision of the tumor, curettage of underlying bone surface, and extraction of right lower D under general anesthesia. Post-operative course has been uneventful without local recurrence for 3 years and 6 months.

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