ウサギでのチタンメッシュを使った骨・骨膜間拡大による骨誘導についての実験的研究

  • 原 純一
    東北大学大学院歯学研究科口腔病態外科学講座顎顔面外科学分野
  • 根井 仁志
    東北大学大学院歯学研究科口腔病態外科学講座顎顔面外科学分野
  • 川村 仁
    東北大学大学院歯学研究科口腔病態外科学講座顎顔面外科学分野

書誌事項

タイトル別名
  • The possibility to form new bone by using osteogenesis devices placed between bone and periosteum in rabbits
  • ウサギ デノ チタン メッシュ オ ツカッタ ホネ コツマクカン カクダイ ニ ヨル コツ ユウドウ ニ ツイテ ノ ジッケンテキ ケンキュウ

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抄録

A healing space is created between the periosteum and the bone while ablating the periosteum and suturing it again to its own position. However, there are no reports mentioning that the healing space can be expanded gradually with the possibility of inducing the formation of new bone. This study examined the possibility of forming new bone by using osteogenesis devices in the healing space.<BR>Material and methods: 25 rabbits were used and divided into control and experiment groups; both groups underwent periosteum ablation with an osteogenesis device placed in the healing space of the control group, then the periosteum was sutured in both groups to its own position.<BR>Results: The control groups showed revascularization with thin new bone formed in the healing space. On the other hand, all the experimental groups showed expansion in the healing space, with more revascularization beside the original bone compared to the side of the periosteum. The first experimental group was observed after one week of ceasing expansion, and the histological findings showed new bone formation over original bone. In the 2-week and 4-week -groups, the new bone showed much more maturation than the 1-week group.<BR>Conclusion: It can be concluded that gradually expanding the healing space between the periosteum and bone might induce the formation of new bone over the original bone surface in the healing space.

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