Analysis of developmental mechanism to regenerate salivary gland

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  • SAKAI Takayoshi
    The First Department of Oral&Maxillofacial Surgery, Osaka University Graduate School of Dentistry
  • KOGO Mikihiko
    The First Department of Oral&Maxillofacial Surgery, Osaka University Graduate School of Dentistry

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Other Title
  • 唾液腺再生をめざした発生機構の解析
  • ダエキセン サイセイ オ メザシタ ハッセイ キコウ ノ カイセキ

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Abstract

Recently, clinicians and scientists have focused on tis sueengineering for regenerative medical therapy. This approach promises to provide remarkable clinical break throughsfor the future. In oral and craniofacial medi cine, most scientific approaches to tissue engineering currently involve tooth and bone, while little progress has been made toward regenerating organs such as the salivary gland. To develop strategies for salivary gland regeneration, it will be important to understand the molecular mechanisms of normal salivary development. This research describes a recently developed and tested set of approaches for identifying and characterizing mol eculesessential for branching morphogenesis and other developmental processes using both of laser microdissec tionand T7-SAGE.

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