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- KUMAGAI Isoa
- The Third Department of Medicine Okayama University Medical School
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- TAKATORI Katsuhiko
- The Third Department of Medicine Okayama University Medical School
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- NISHIMURA Masaaki
- The Third Department of Medicine Okayama University Medical School
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- THENG Long Zhu
- The Third Department of Medicine Okayama University Medical School
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- TAKAOKA Michio
- The Third Department of Medicine Okayama University Medical School
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- MAKINO Hirofumi
- The Third Department of Medicine Okayama University Medical School
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- TAKAHASHI Kayo
- The Third Department of Medicine Okayama University Medical School
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- MIYAWAKI Shoji
- The Third Department of Medicine Okayama University Medical School
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- OTA Zensuke
- The Third Department of Medicine Okayama University Medical School
Bibliographic Information
- Other Title
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- 混合性結合組織病(MCTD)の経過中急速に腎障害をきたした1例
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Description
40才,女性.混合性結合組織病(MCTD)で経過観察中にネフローゼ症候群,腎機能低下をきたした.腎生検では膜性変化,巣状増殖性変化と小血管の軽度の肥厚を認めた.ステロイド薬治療中に高血圧,血尿・蛋白尿の増加,腎機能の低下,レニン活牲の上昇をきたし,カプトプリルの投与により改善が得られた. MCTDの腎病変は比較的軽度のものが多いが,急速に腎不全に陥る例もみられ,この症例も含めて強皮症腎様の血管病変の進行が示唆される.
Journal
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- Nihon Naika Gakkai Zasshi
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Nihon Naika Gakkai Zasshi 78 (6), 846-847, 1989
The Japanese Society of Internal Medicine