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- Saito Bunichi
- Dept. of Int. Med. School of Med. Keio Univ.
Bibliographic Information
- Other Title
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- ペーパークロマトグラフイーによる尿中アミノ酸の研究
- ペーパークロマトグラフイー ニ ヨル ニョウチュウ アミノサン ノ ケンキュウ
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Abstract
Amino-acids in urine were analyzed by means of paper partition chromatograph, both clinically and experimentally.<br>Usually two-dimension method is performed, but it is also of some clinical value to detect amino-acids with large Rf by the use of one dimension method.<br>Alanine, Glycine and Taurine always appear in urine, no matter whether it be normal or pathological.<br>As a rule, amino-acids detected in urine of hepatic patients increase in number; especially in the jaundice-stage of acute hepatitis there can be ascertained several sorts of amino-acids, while in the reconvalescence they decrease in number showing tendency to become normal.<br>In cases with liver cirrhosis, detected amino-acids are of various number, only the appearance of amino-acids with large Rf is more remarkable than in those who suffer from hepatitis. This occurrence is neither concerned in existence of icterus nor ascites.<br>In cases with hepatic coma, some increase in number very much, others not so markedly. That is to say, patients suffering from hepatic coma do not always excrete high-degree amino-aciduria.<br>Number of amino-acids proved in hepatic cancer is relatively few, and there is no great difference between in cancer and innormal.<br>Number of amino-acids detected in cholecystitis and cholecystopathy fluctuates instablely. In above mentioned cases there can not be proved any special amino-acid appearing without fail.<br>Attitude of amino-acids in urine of rats which livers were damaged with various kinds of toxins, is similar to that of clinical cases.<br>High protein diet after administration of hepatic toxins is admitted as effective to prevent the appearance of a certain amino-acids in urine.
Journal
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- Nihon Naika Gakkai Zasshi
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Nihon Naika Gakkai Zasshi 43 (12), 981-989, 1955
The Japanese Society of Internal Medicine
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Keywords
Details 詳細情報について
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- CRID
- 1390001206443660032
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- NII Article ID
- 130000883781
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- NII Book ID
- AN00195836
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- ISSN
- 18832083
- 00215384
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- NDL BIB ID
- 10059736
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed