Focal Adenocarcinoma Arising from Sessile Serrated Adenoma/Polyp with Intestinal Spirochetosis, Report of a Case

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  • Omori Saori
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine
  • Mabe Katsuhiro
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine Department of Endoscopy, Hokkaido University Hospital
  • Ono Masayoshi
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine
  • Suzuki Mio
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine
  • Takahashi Masakazu
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine
  • Ono Shoko
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine Department of Endoscopy, Hokkaido University Hospital
  • Simizu Yuichi
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine
  • Kato Mototsugu
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine Department of Endoscopy, Hokkaido University Hospital
  • Hatanaka Kanako
    Department of Surgical Pathology, Hokkaido University Hospital
  • Sakamoto Naoya
    Department of Gastroenterology, Hokkaido University Graduate School of Medicine

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Other Title
  • 粘膜内癌を合併したSSA/Pに腸管スピロヘータが確認された1例
  • 今月の症例 粘膜内癌を合併したSSA/Pに腸管スピロヘータが確認された1例
  • コンゲツ ノ ショウレイ ネンマク ナイガン オ ガッペイ シタ SSA/P ニ チョウカン スピロヘータ ガ カクニン サレタ 1レイ

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Abstract

大腸癌の発育進展経路として鋸歯状病変からの癌化であるserrated pathwayが新しく提唱されている．BRAF変異の関与が考えられているが，遺伝子変異の原因やリスクファクターについてはまだ解明されていない．今回，粘膜内癌を合併したSSA/Pに腸管スピロヘータを確認した．ヒトの腸管スピロヘータがSSA/Pの発生，癌化に関連がある可能性もあり貴重な症例と考え報告した．

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