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- 間瀬 南
- 名古屋市立大学医学部細菌学数室
書誌事項
- タイトル別名
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- Germination and Outgrowth of Spores and Proliferation of Outgrown Vegetative Cells in the Peritoneal Cavity of Mice Intraperitoneally Injected with <i>Bacillus cereus</i> or <i>Bacillus subtilis</i> Spores
- マウス フククウナイ ニ オケル Bacillus cereus オヨビ Ba
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To explore the toxicity of Bacillus cereus, the fate of spores injected into the mouse peritoneal cavity was compared between this organism and Bacillus subtilis.<br>One hour after injection of about 1.8×109 spores of B. cereus, most of the spores were found to have been phagocytized by phagocytic cells and a few as germinated ones in the peritoneal cavity. Two hours after injection, the germinated spores began to outgrow. Outgrown vegetative cells started to proliferate. Three hours after injection, they showed a marked proliferation, while some of them and some germinated spores were engulfed by phagocytic cells. By that time the peritoneal cavity was filled with proliferating vegetative cells. All the mice died during a period from 4 to 6 hours after injection.<br>The MLD of B. cereus spores for mice by the intraperitoneal route was calculated as 4.35×108.<br>In contrast, when about 1.6×109 spores of B. subtilis were injected intraperitoneally to mice, some of them germinated in the peritoneal cavity, and only a few of them were able to outgrow. Outgrown vegetative cells hardly proliferated. Thus no death occurred to the mice injected with B. subtilis spores.
収録刊行物
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- 日本細菌学雑誌
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日本細菌学雑誌 32 (6), 837-842, 1977
日本細菌学会
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詳細情報 詳細情報について
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- CRID
- 1390001206449835904
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- NII論文ID
- 130001384238
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- NII書誌ID
- AN00189800
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- ISSN
- 18824110
- 00214930
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- NDL書誌ID
- 1916097
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- PubMed
- 415160
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可