細胞-抗酸菌感染系に関する研究

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タイトル別名
  • Cell-Mycobacteria-Infection System
  • サイボウ コウサンキン カンセンケイ ニ カンスル ケンキュウ 2
  • II. Studies on the factors influencing phagocytosis of Mycobacteria by L cells, especially the effect of old tuberculin treatment to the cells
  • 第2報L細胞の抗酸菌食菌に影響を与える因子ことにツベルクリンについて

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The effects of pretreatment of BCG-old tuberculin (OT) to the L cells and the presence of BCG-oldtuberculin in the culture media on the infection of BCG to the cells were studied and the following resultswere obtained:<BR>1. Pretreatment of BCG-old tuberculin to the cells stimulated phagocytosis of Mycobacteria by the Lcells. The phagocytosis rate was increased especially when 10-1 or 10-2 concentration of old tuberculin was.used for treatment to the cells which were cultivated for more than 48 hours.<BR>2. It was demonstrated by the immunological method using skin reaction that BCG old-tuberculin.pretreated was bound to the cells, but it could not be found what kind of effect of tuberculin enhanced thephagocytosis of Mycobacteria by the L cells and that there was any immunological relationship betweentuberculin and bacilli in the case of phagocytosis.

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