書誌事項
- タイトル別名
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- Clinical Application of TKD-36 (Moku-boi-to) on Chronic Heart Failure in Dogs.
- イヌ ノ マンセイ シンフゼン ニ タイスル TKD-36 モクボイトウ ノ
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抄録
A multi-central clinical trial was conducted to assess the effect of TKD-36 (Moku-boi-to)on chronic heart failure in dogs. TKD-36 (75, 150 or 300 mg/kg/day, divided b. i. d., p. o.) or placebo were administered for 4 weeks to dogs showing signs of chronic heart failure. Overall assessment and various clinical evaluation of clinical symptoms in dogs treated with TKD-36 (150 and 300 mg/kg/day) were excellent compared to that in dogs treated with the placebo. But the dose of 75 mg/kg/day of TKD-36 did not improve any clinical signs of heart failure as same as the placebo group. No adverse reactions attributable to TKD-36 administration were observed, confirming its safety in this species. Based on efficacy, safety and overall assessment analyses, the optimal dosage of TKD-36 is from 150 to 300 mg/kg/day.<BR>These results clearly indicate that TKD-36 is an excellent drug for a treatment of the chronic heart failure in dogs.
収録刊行物
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- 動物の循環器
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動物の循環器 29 (2), 59-78, 1996
日本獣医循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390001206457195392
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- NII論文ID
- 10008286971
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- NII書誌ID
- AN10192925
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- ISSN
- 18835260
- 09106537
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- NDL書誌ID
- 4107691
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可