書誌事項
- タイトル別名
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- Intracerebroventricular Injection of Glucagon-Like Peptide-1 Inhibits Water Intake of the Neonatal Chick.
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The aim of present study was to elucidate whether central injection of GLP-1 modifies water intake of chicks under dehydration or angiotensin II (AII) treatment. Birds (2-day-old) with or without 19-h dehydration were given diets and then GLP-1(30ng/10μl) or saline was injected to birds in both treatments by the intracerebroventricular (i.c.v.) route in experiment 1. Irrespective of drinking conditions GLP-1 inhibited water consumption for 1h; the inhibitory effect of water intake by GLP-1 was strong in the dehydrated birds. Central administration of AII (0, 25, 50 and 100ng) increased water intake for 30min in a dose dependent manner when water given ad libitum in experiment 2. Thereafter, the relationships between i.c.v. GLP-1 and AII on water intake was investigated in experiment 3. Water intake was decreased by co-injection with GLP-1 (30ng) and AII (100ng).<br>These results suggest that central GLP-1 may be the regulator of water intake in the neonatal chick.
収録刊行物
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- 日本家禽学会誌
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日本家禽学会誌 36 (4), 229-235, 1999
日本家禽学会
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詳細情報 詳細情報について
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- CRID
- 1390001206457761536
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- NII論文ID
- 10009950648
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- NII書誌ID
- AN00186755
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- NDL書誌ID
- 4812759
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- ISSN
- 00290254
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可