硬骨魚類のToll様受容体システム

DOI 日本農学文献記事索引 Web Site 被引用文献5件 参考文献191件
  • Takano Tomokazu
    Aquatic Animal Health Division, National Research Institute of Aquaculture, Fisheries Research Agency
  • Hwang Seong Don
    Laboratory of Genome Science, Tokyo University of Marine Science and Technology
  • Kondo Hidehiro
    Laboratory of Genome Science, Tokyo University of Marine Science and Technology
  • Hirono Ikuo
    Laboratory of Genome Science, Tokyo University of Marine Science and Technology
  • Aoki Takashi
    Laboratory of Genome Science, Tokyo University of Marine Science and Technology
  • Sano Motohiko
    Aquatic Animal Health Division, National Research Institute of Aquaculture, Fisheries Research Agency

書誌事項

タイトル別名
  • Evidence of Molecular Toll-like Receptor Mechanisms in Teleosts

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抄録

Toll-like receptors (TLRs) recognize the pathogen-associated molecular patterns (PAMPs) and play a pivotal role in modulating the immune response against invading pathogens. To date, many teleost TLRs have been identified by genome and transcriptome analysis. The orthologs involved in the TLR signalings have also been identified in teleosts. The comparison of the TLR functions in teleosts and mammals may provide significant information that will aid our understanding of host-pathogen interactions in teleosts. In this paper, we summarize of the literature regarding teleost TLRs, focusing on the similarities and differences between TLR mechanisms in teleosts and mammals. In addition, perspectives for future studies on teleost TLRs and the application of TLRs to aquaculture are discussed.

収録刊行物

  • 魚病研究

    魚病研究 45 (1), 1-16, 2010

    日本魚病学会

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