Studies on a New Virus(OMV)from Oncorhynchus masou-2-Oncogenic Nature

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タイトル別名
  • Studies on a New Virus (OMV) from Oncorhynchus mason-II.
  • Studies on a New Virus OMV from Oncorhy
  • Studies on a new virus (OMV) from Oncorhynchus masou-II: oncogenic nature
  • Oncogenic Nature

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説明

Among survivors of experimental infection of herpesvirus OMV which was considered to be a new viral pathogen of salmonids producing hepatic necrosis and significant mortality, more than 60% developed tumors. The perioral maxillary and mandibular region are the most frequent site of tumor formation. In decreasing order of frequency, tumors were also found on the caudal fin, gill-cover, eye, and kidney.<BR>Histopathologically the tumors were composed of abundantly proliferative, well differentiated epithelial cells supported by fine connective tissue stroma.<BR>Although virus particles were not observed in tumor cells, OMV isolation was successful from a tumor tissue sample that appeared necrotic on day 275 postinfection and from primary cultures of a tumor tissue from another fish sampled 296 days postinfection.<BR>From the evidence thus far obtained, OMV is considered to be a new pathogenic and oncogenic salmon virus.<BR>It is the first oncogenic agent to be isolated from fish.

収録刊行物

  • 魚病研究

    魚病研究 15 (3-4), 149-153, 1981

    日本魚病学会

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