Studies on bilirubin metabolism in fish. III. Changes in bilirubin contents and composition in the bile of starved and CCl4 injected carp.

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  • 魚類におけるビリルビン代謝 III  コイの絶食時および四塩化炭素投与時における胆汁中bilirubin含量と組成の変動
  • コイ ノ ゼッショクジ オヨビ 4 エンカ タンソ トウヨジ ニ オケル タン
  • Studies on bilirubin metabolism in fish-III

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Abstract

Changes in bilirubin contents and composition in the bile of starved and CCl4 injected carp Cyprinus carpio were examined by diazo methods. The doses of CCl4 injection were 10, 40, and 100μl/100g body weight.<BR>In the bile of control carp, total, conjugated, and unconjugated bilirubin contens were 0.03-0.13, 0.02-0.08, and 0.01-0.02 mg /ml, respectively. During the starvation, total and conjugated bilirubin contents gradually increased but unconjugated bilirubin contents did not change. After 30 days, total and conjugated bilirubin contents were 22-26 times higher than those of control.<BR>In the bile of CCl4 injected carp, total and conjugated bilirubin contents increased rapidly. Both contents were 8-18 times higher than those of control one day after injection. Unconjugated bilirubin contents in carps injected with 40μl and 100μl CCl4 were increased 5 days and 2 days after injection, respectively.

Journal

  • Fish Pathology

    Fish Pathology 20 (4), 469-473, 1985

    The Japanese Society of Fish Pathology

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